Is Lion’s Mane Beneficial for Gut Health?

Is Lion’s Mane Beneficial for Gut Health?

Lion's mane mushrooms contain beneficial compounds that may support gut health. These compounds promote the growth of healthy bacteria in the digestive system, which can strengthen your immune system. Additionally, lion's mane may help prevent the growth of H. pylori, a harmful bacteria linked to stomach ulcers.

Digestive problems are incredibly common, affecting countless individuals and impacting their quality of life. From uncomfortable bloating and gas to the pain and discomfort of gastritis or the frustrating irregularity of IBS, a troubled gut can seriously disrupt everyday life. While conventional treatments exist, many people seek natural alternatives. Enter Lion's Mane mushroom, a fascinating fungus with a long history in traditional medicine and growing interest within the scientific community. Could this unique mushroom hold the key to better digestive health?

What is Lion's Mane Mushroom?

With its distinctive cascading spines, Lion's Mane mushroom truly looks like its namesake. Beyond its quirky appearance, it's a popular culinary mushroom and has been used in traditional medicine for centuries.  While a delicious addition to your plate, Lion's Mane also contains a treasure trove of bioactive compounds, such as polysaccharides, hericenones, and erinacines, which may be the reason behind its potential digestive benefits. It's these unique compounds that have piqued the interest of researchers looking into the ways Lion's Mane might support a healthier gut.

Lion's Mane and Gastritis

Gastritis refers to inflammation of the stomach lining. It can cause a gnawing or burning pain in the upper abdomen, alongside symptoms like nausea, vomiting, and a feeling of fullness after eating. Common causes of gastritis include infection with Helicobacter pylori (H. pylori) bacteria, overuse of pain relievers like ibuprofen (a type of NSAID), and excessive alcohol consumption.

How Lion's Mane Might Help

Emerging research suggests Lion's Mane could hold promise for those with gastritis. Here's how it might potentially help:

  • Promote Gut Lining Repair: Gastritis damages the protective lining of the stomach, and some research suggests Lion's Mane could help stimulate its repair. This could reduce inflammation and relieve gastritis symptoms.
  • Anti-inflammatory Properties: Lion's Mane possesses anti-inflammatory compounds. Reducing inflammation in the stomach is a key part of managing gastritis.

Important Note: Although these findings are promising, more human-focused research is needed to confirm Lion's Mane's effectiveness specifically for gastritis.

Lion's Mane and IBS

Irritable bowel syndrome (IBS) is a frustratingly common gut disorder affecting the large intestine. Its symptoms can include abdominal pain, cramping, bloating, gas, constipation, and/or diarrhea.  IBS has several subtypes depending on the main symptoms, and while its exact causes are unknown, stress, diet, and changes in gut bacteria can all play a role.

How Lion's Mane Might Help

Lion's Mane could potentially offer relief for those with IBS in a few ways:

  • Support a Healthy Gut Microbiome: Our gut is home to a complex community of bacteria, and an imbalance in these microbes can contribute to IBS symptoms. Lion's Mane seems to support a healthy bacterial balance in the gut, which could help reduce IBS discomfort.
  • Decrease Gut Inflammation: Inflammation in the gut is often seen in those with IBS. Lion's Mane's anti-inflammatory properties have the potential to soothe this inflammation, leading to improved IBS symptoms.
  • Reduce IBS-Related Stress and Anxiety: The gut and the brain are closely connected, and stress and anxiety can worsen IBS symptoms. Lion's Mane's potential calming effects might help lessen IBS flare-ups triggered by those mental health factors.


Lion's Mane for Overall Digestion

Beyond Gastritis and IBS

 While the potential benefits for  gastritis and IBS are exciting, Lion's Mane might offer broader support for overall digestive health. Here's how:

  • Reducing Bloating and Gas: Lion's Mane might help reduce uncomfortable bloating and excess gas by promoting a healthy balance of gut bacteria and improving digestive processes.
  • Promoting Healthy Bowel Movements: By supporting gut health and potentially having mild prebiotic effects, Lion's Mane could contribute to more regular and comfortable bowel movements.
  • Prebiotic Effects: Prebiotics act as "food" for beneficial gut bacteria. Early research hints that Lion's Mane may have prebiotic properties, which could further boost gut health and overall digestion.

What the Scientific Data Says

Recent studies are shedding light on the potential of Lion's Mane mushroom to promote a healthier gut.  Let's look at two key studies and what their findings could mean:

Study 1: Alleviation of Inflammatory Bowel Disease (IBD)

  • Objective: This study* aimed to investigate whether different Lion's Mane extracts could improve IBD symptoms in a rat model.
  • Findings: Lion's Mane extracts led to significant improvements in both symptoms and tissue health. Researchers noted enhanced immunity, reduced inflammation, and a shift in gut bacteria favoring beneficial microbes.
  • What This Means for Gut Health: These results suggest Lion's Mane could help manage IBD symptoms through several mechanisms. The prebiotic effect of its polysaccharides supports the growth of healthy gut bacteria, while its alcoholic extracts appear to directly fight harmful microbes and balance the immune response.
A diagram showing the findings from a study on the effects of Lion's mane mushroom on IBD symptoms

Study 2: Inhibition of Helicobacter Pylori

  • Objective: Researchers tested** if Lion's Mane extracts could inhibit H. pylori, the bacteria associated with gastritis and ulcers, without harming beneficial gut microbes.
  • Findings: Lion's Mane extracts powerfully inhibited H. pylori growth, prevented it from attaching to stomach cells, and reduced inflammation and DNA damage caused by the bacteria. In a mouse model, Lion's Mane lowered H. pylori levels in the stomach.
  • What This Means for Gut Health: This study indicates that Lion's Mane could be a natural tool for combating H. pylori infections. By directly inhibiting the bacteria and protecting stomach cells, it has the potential to alleviate gastritis and reduce the risk of ulcers.
A flowchart showing the findings from a study on how Lion's mane inhibits symptoms of H.Pylori

Summary Table of Findings



Key Findings


Study 1: IBD Alleviation

Investigate Lion's Mane extracts in treating IBD

Significant improvement in IBD symptoms

Polysaccharides show prebiotic effects; alcoholic extracts have bacteria-fighting and immune-balancing effects

Study 2: H. Pylori Inhibition

Assess extracts against Helicobacter pylori

Potent inhibitory effects on H. pylori growth

Potential natural agent for managing H. pylori-related gastric issues; reduces H. pylori levels and associated damage

How to Use Lion's Mane for Digestive Health

Dosage and Safety

While Lion's Mane is generally considered safe, it's crucial to consult your doctor before incorporating it into your health routine. This is especially important if you have any existing medical conditions or take medications.  Typical dosages used in research for digestive health range from 1000mg to 3000mg daily.

(Our premium Lion’s Mane supplement “Cognition” comes in a 12:1 extract dosage equivalent to 1500mg per serving, check it out here).

Forms of Lion's Mane

Lion's Mane is available in several forms:

  • Capsules: A simple and convenient option for taking Lion's Mane.
  • Extracts: These may offer a more concentrated dose of active compounds.
  • Powders: Powders are versatile and can be mixed into smoothies, soups, or other foods and beverages.

When choosing a Lion's Mane supplement, opt for reputable brands that are transparent about their sourcing, extraction methods, and product purity.

Potential Side Effects

Lion's Mane is typically well-tolerated, but mild digestive upset can occur in some individuals. Those with known mushroom allergies should avoid Lion's Mane. If you experience any side effects, stop taking Lion's Mane and consult your doctor.

Lion's Mane: A Natural Path to Gut Relief?

The research surrounding Lion's Mane and its potential benefits for gut health is incredibly promising. Its ability to fight harmful microbes, protect the stomach lining, support healthy gut bacteria, and reduce inflammation could offer natural relief for conditions like gastritis, IBS, and overall digestive discomfort.  While more human studies are needed to fully understand its effects, Lion's Mane could be a valuable addition to your digestive health toolkit alongside healthy lifestyle practices.

As always, consult your doctor before starting Lion's Mane or any new supplement, especially if you have underlying health conditions or take medications.

If you're interested in exploring the potential benefits of Lion's Mane, consider trying our premium Lion's Mane supplement “Cognition”. It’s sustainably sourced, carefully extracted for maximum potency, and designed to support optimal digestive health.

Quality and Trust: The Mushroom Works Difference

Finding reputable Lion’s Mane supplements can be a challenge in a market with varying regulations. At Mushroom Works, we understand the importance of quality and transparency. That's why:

  • UK-Based Manufacturing: All of our products are manufactured in the UK to GMP standard, guaranteeing consistent high quality and safety.
  • In-House Expertise: Our supplier uses an in-house regulatory team to ensure any products we make are fully compliant, giving you complete peace of mind.

Choosing Mushroom Works means choosing a brand committed to providing the best possible supplements to support your health journey.

Studies & References

  • *Diling C, Xin Y, Chaoqun Z, Jian Y, Xiaocui T, Jun C, Ou S, Yizhen X. Extracts from Hericium erinaceus relieve inflammatory bowel disease by regulating immunity and gut microbiota. Oncotarget. 2017 Sep 6;8(49):85838-85857. doi: 10.18632/oncotarget.20689. PMID: 29156761; PMCID: PMC5689651.
  • **Wang G, Zhang X, Maier SE, Zhang L, Maier RJ. In Vitro and In Vivo Inhibition of Helicobacter pylori by Ethanolic Extracts of Lion's Mane Medicinal Mushroom, Hericium erinaceus (Agaricomycetes). Int J Med Mushrooms. 2019;21(1):1-11. doi: 10.1615/IntJMedMushrooms.2018029487. PMID: 30806251. 
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