Lion's Mane Mushroom: A Guide to Dosage and Benefits

Lion's Mane Mushroom: A Guide to Dosage and Benefits

The recommended daily dosage of Lion's Mane powder typically ranges from 1 to 3 grams. For a 12:1 extract, this would be equivalent to a minimum of 80mg, a mid-Range of 125mg and a maximum of 250mg.

Lion's Mane Dosages for Specific Conditions

Here's a table providing a general overview of Lion's Mane dosages reported in research and anecdotal evidence.  Remember, these are starting points, and individual needs may vary.

Lion's Mane for

Dosage Range


Depression and Anxiety

750mg - 5000mg daily

Some individuals report benefits at higher dosages

Cognitive Function

750mg - 1000mg daily

Start with a lower dose and increase as needed

Dementia and Alzheimer's Disease

1000mg daily

Studies suggest this dosage, with the potential to increase


2000mg - 5000mg daily

Consult a doctor, especially if using with medications


500-1000mg, 1-3 times daily

May promote nerve regeneration and reduce pain


Important Considerations:

  • Consulting a Doctor: This table is for informational purposes. It's crucial to consult a healthcare professional, especially if you have any existing health conditions or are taking medications.
  • Individual Response: Everyone responds differently to supplements. Start with a lower dosage and gradually adjust based on your individual needs and tolerance.
  • Quality Matters: Choose reputable brands and ensure your Lion's Mane products are third-party tested for purity and potency.

Lion's Mane (Hericium erinaceus) has been gaining popularity for its potential to support brain health, improve mood, and reduce inflammation. Early studies and anecdotal evidence suggest that Lion's Mane might offer health benefits for various conditions.

One common question is "How much Lion's Mane should I take?" The optimal dosage depends on several factors, including your individual needs, health goals, and the form of Lion's Mane you choose.  It's always best to consult with a healthcare professional for personalised guidance before starting any new supplement.

General Lion's Mane Mushroom Dosage Guidelines

  • Starting Dosage: A typical starting dosage of Lion's Mane ranges from 750-1000 mg daily. Begin at the lower end of this range and observe how your body responds.
  • Gradual Increase: If you don't notice the desired effects after a few weeks, you can gradually increase your dosage. Listen to your body and adjust accordingly under the guidance of a healthcare provider.
  • Forms: Lion's Mane is available in various forms, including capsules, powders, extracts, and even fortified foods like granola or coffee. The specific dosage may vary slightly depending on the product's concentration and form.

    Lion's Mane Dosages for Other Conditions

    • Multiple Sclerosis (MS): Lion's Mane shows promise for MS due to its neuroprotective and regenerative properties. Higher dosages may be beneficial (e.g., upwards of 1000mg daily). Consult a healthcare professional familiar with MS and natural remedies.
    • Parkinson's Disease: Research suggests starting at 250mg and increasing to around 3000mg daily for potential benefits in reducing symptoms and slowing disease progression.
    • Overall Health Maintenance: If using Lion's Mane for general wellness, antioxidant support, and its neurotrophic effects, a lower daily dosage (250-750 mg) may be sufficient.

    The Best Way to Take Lion's Mane


    Supplemental Lion's Mane is available in several forms, influencing the optimal dosage. Here's what you need to know:

    • Capsules: Offer a precise and convenient way to take Lion's Mane. Follow the specific dosage instructions on the product label.
    • Powders: Ideal for adding to smoothies, drinks, or food. Dosages are typically listed in grams. Start with 1-2 grams daily and adjust based on your needs.
    • Extracts: These are the most concentrated forms of Lion's Mane. Exercise caution, as the dosages are typically lower than powders or capsules. Look for products with standardised extract percentages for consistency.

    Fortified Foods

    Options like mushroom granola, coffee, and tea provide an easy way to incorporate Lion's Mane into your diet. 


    If you can find fresh Lion's Mane, experiment with adding it to recipes. Note that its taste can be strong.

      The Best Time to Take Lion's Mane

      While there's no one-size-fits-all answer, most people take lion's mane daily, consider these factors when deciding the best time to take Lion's Mane:

      • Desired Effects:
        • Focus and Cognitive Boost: A morning dose might align well with its potential to enhance concentration and mental clarity.
        • Relaxation and Sleep Support: If you find Lion's Mane promotes calmness, an evening dose could be beneficial for winding down before bed.
      • Individual Sensitivity: Some people are more sensitive to supplements than others. Start with a smaller dose and observe how you feel. If you experience any jitters or alertness at night, switching to morning intake might be preferable.
      • Empty Stomach vs. With Meals: There's no definitive research on this. Experiment to see if taking Lion's Mane on an empty stomach or with food impacts how it makes you feel.

      Potential Drug Interactions

      Lion's Mane, while generally safe, has potential interactions that require serious consideration:

      • Blood Thinners (Anticoagulants and Antiplatelets): Lion's Mane might slow blood clotting. Combining it with blood thinners could increase the risk of bruising and bleeding.
      • Diabetes Medications: Due to its potential blood-sugar-lowering effects, Lion's Mane could interact with diabetes medications. Close blood sugar monitoring is essential if you are diabetic and considering Lion's Mane.
      • Immune System Medications (Immunosuppressants): Lion's Mane might boost immune function, potentially interfering with medications designed to suppress the immune system (often used after organ transplants).

      Important Note: This list is NOT exhaustive. It's imperative to disclose ALL medications (prescription, over-the-counter, and any other supplements) to your doctor before starting Lion's Mane.

      Stacking with Other Mushrooms

      Lion's Mane demonstrates potential synergy when paired with other functional mushrooms. Always consult a knowledgeable healthcare professional before creating your own mushroom stack, but here are some popular combinations and their theorised benefits:

      • Lion's Mane + Cordyceps: This stack could offer enhanced energy, athletic performance, and mental focus. Cordyceps is known for its potential to boost oxygen utilisation and reduce fatigue.
      • Lion's Mane + Reishi: Pairing these mushrooms might promote relaxation, stress reduction, and improved sleep quality. Reishi is often touted as the "mushroom of immortality" for its potential calming and immune-supporting properties.
      • Lion's Mane + Chaga: This combination could provide a potent dose of antioxidants and immune support. Chaga is rich in compounds that may protect cells from damage and reduce inflammation.

      Our potent mushroom blend “Thrive” combines all of these mushrooms and more! It’s a fantastic option for people looking for a one-stop functional mushroom solution!

      Subjective Experience

      Tracking your individual response to Lion's Mane is vital for optimising benefits.  Consider keeping a detailed journal that notes:

      • Mood: Does Lion's Mane lift your mood, reduce anxiety, or promote a sense of calmness?
      • Mental Clarity: Do you notice improvements in focus, memory, or your ability to process information?
      • Energy Levels: Does it have a stimulating effect, help reduce fatigue, or simply stabilise your energy throughout the day?
      • Sleep Quality: Does Lion's Mane influence the ease of falling asleep, sleep duration, or vividness of dreams?
      • Other Observations: Note any other changes, such as digestion, appetite, or physical sensations.

      This personalised log may reveal patterns and help you fine-tune your Lion's Mane usage to work best for your specific needs!

      Safety and Precautions

      • Side Effects: Lion's Mane is generally well-tolerated, but some people might experience mild digestive discomfort, especially when starting with higher dosages. Start low and increase gradually.
      • Interactions: It's important to inform your doctor about all medications and supplements you take, as Lion's Mane might interact with certain drugs.
      • Long-term Use: Daily Lion's Mane consumption appears safe and beneficial for many. The potential benefits often become more pronounced with consistent use.

      Your Path to Optimal Lion's Mane Benefits

      Lion's Mane offers a fascinating natural approach to supporting your health and well-being.  Finding the right Lion's Mane dosage takes some experimentation and guidance from a qualified healthcare professional.  By starting slowly,  monitoring your response, and choosing high-quality products, you can explore the potential benefits of this remarkable mushroom.

      Interested in trying Lion's Mane? Our new mushroom supplement “Cognition” contains a healthy dose of Lion's Mane extract alongside selected adaptogens.


      1. Mori, K (2011). Effects of Hericium erinaceus on amyloid β(25-35) peptide-induced learning and memory deficits in mice
      2. Saitsu, Y. (2019). Improvement of cognitive functions by oral intake of Hericium erinaceus
      3. Mori, K. (2009) Improving effects of the mushroom Yamabushitake (Hericium erinaceus) on mild cognitive impairment: a double-blind placebo-controlled clinical trial
      4. Wong, K-H (2011) Peripheral Nerve Regeneration Following Crush Injury to Rat Peroneal Nerve by Aqueous Extract of Medicinal Mushroom Hericium erinaceus (Bull.: Fr) Pers. (Aphyllophoromycetideae)
      5. Wong, K-H. (2007) Activity of Aqueous Extracts of Lion's Mane Mushroom Hericium erinaceus (Bull.: Fr.) Pers. (Aphyllophoromycetideae) on the Neural Cell Line NG108-15
      6. Lee, K-F. (2020) Post-Treatment with Erinacine A, a Derived Diterpenoid of H. erinaceus, Attenuates Neurotoxicity in MPTP Model of Parkinson’s Disease


      What are the potential health benefits of Lion's Mane mushroom?

      Lion's Mane mushroom may have beneficial effects on nerve growth, cognitive function, and the reduction of depression and anxiety.

      How much Lion's Mane mushroom should I take daily?

      The proper Lion's Mane dosage may vary depending on the form of the supplement. Generally, it is recommended to take 500-3000 mg of Lion's Mane mushroom extract or powder per day.

      How long does it take to see the effects of Lion's Mane mushroom?

      Some studies suggest that Lion's Mane may help reduce depression and anxiety after 4 weeks of consistent use. However, the time to see beneficial effects may vary among individuals.

      Can I consume Lion's Mane mushroom as a food?

      Yes, Lion's Mane mushrooms have been consumed for centuries in traditional medicine and cuisine. The fruiting bodies of the mushroom can be cooked and eaten.

      Is Lion's Mane mushroom legal?

      Yes, Lion's Mane is legal and widely available as a dietary supplement in many countries.

      What forms of Lion's Mane supplements are available?

      Lion's Mane supplements are available in various forms, including extracts, powders, and capsules. The most common form is the extract, which is often standardised to contain specific levels of beneficial compounds.

      Are there any adverse effects associated with taking Lion's Mane mushroom?

      Lion's Mane is generally considered safe when taken in recommended doses. However, some people may experience mild side effects such as digestive discomfort. It is always best to consult with a healthcare professional before starting any new supplement regimen.

      Can Lion's Mane mushroom improve cognitive function?

      Some studies suggest that Lion's Mane may improve cognitive function, particularly in older adults. Animal studies have also shown that Lion's Mane can improve memory in wild-type mice.

      How long has Lion's Mane been used for medicinal purposes?

      Lion's Mane has been used for centuries in traditional Chinese medicine for its potential health benefits. It is known as a medicinal mushroom and has been used to support overall health and wellbeing.

      What does Lion's Mane mushroom contain that may contribute to its health benefits?

      Lion's Mane contains several beneficial compounds, including hericenones and erinacines, which are believed to stimulate nerve growth factor (NGF) synthesis. NGF is essential for the growth, maintenance, and survival of neurones.

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